The JAK2-STAT pathway epigenetically regulates tolerized genes during the first encounter with bacterial antigens
C. Lorente-Sorolla, O. Morante-Palacios, A. Garcia-Gomez, L. Ciudad, F. Catala-Moll, A. Ruiz-Sanmartin, M. Martinez-Gallo, R. Ferrer-Roca, J. C. Ruiz-Rodriguez, D. Alvarez-Errico, E. Ballestar
The paper identifies JAK2-STAT pathway involvement in epigenetic regulation of tolerized genes during first bacterial antigen exposure, showing its role in modulating inflammatory responses.
bioRxiv · Oct 16, 2020 · PreprintImmunology