Direct inhibitors of InhA with efficacy similar or superior to isoniazid in novel drug regimens for tuberculosis
L. Encinas, S.-Y. Li, J. Rullas-Trincado, R. Tasneen, S. TYAGI, H. Soni, a. garcia-perez, J. Lee, R. Gonzalez del Rio, J. De Mercado, V. Sousa, I. Sosi?, S. Gobec, A. Mendoza-Losana, P. J. Converse, , E. L. Nuermberger
This study evaluates direct inhibitors of InhA (DIIs) for tuberculosis treatment, showing their efficacy comparable to isoniazid and their potential in new drug regimens.
bioRxiv · Mar 8, 2024 · PreprintPharmacology & Toxicology