S. Abel

WHIRLY1 regulates aliphatic glucosinolate biosynthesis in early seedling development of Arabidopsis

This study shows that WHIRLY1 regulates aliphatic glucosinolate biosynthesis in early Arabidopsis seedling development by affecting gene expression in the biosynthetic pathway.

Multiomics analysis reveals B. MO1 as a distinct Babesia species and provides insights into its evolution and virulence.

The paper identifies B. MO1 as a distinct Babesia species through multiomics analysis, revealing genomic and functional differences from B. divergens and insights into their evolution and virulence.

Toxoplasma gondii F-Box Protein L2 Silences Feline-Restricted Genes Necessary for Sexual Commitment

This paper identifies TgFBXL2, an F-box protein in Toxoplasma gondii, which represses feline-restricted genes required for sexual commitment by modulating SCF-E3 ubiquitin ligase activity.

A Potent Kalihinol Analogue Disrupts Apicoplast Function and Vesicular Trafficking in P. falciparum Malaria.

This paper identifies MED6-189, a potent antimalarial compound that disrupts apicoplast function and vesicular trafficking in P. falciparum, showing efficacy against drug-resistant strains and demonstrating a unique mechanism of action.

PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

This study shows PfMORC regulates chromatin structure and gene repression in Plasmodium falciparum, essential for parasite survival and a potential target for antimalarial drugs.

Plasmodium ARK2-EB1 axis drives the unconventional spindle dynamics, scaffold formation, and chromosome segregation of sexual transmission stages

Plasticity in centromere organization: Holocentromeres can consist of merely a few megabase-sized satellite arrays

The paper analyzes the holocentromere organization in Chionographis japonica, revealing that its holocentromeres consist of few, large satellite arrays and differ from other holocentric species.

Endoplasmic reticulum calnexins participate in the primary root growth response to phosphate deficiency

This study shows that calnexin, an ER lectin chaperone, is involved in primary root growth under phosphate deficiency by regulating Fe-dependent processes.

Deciphering the non-coding code of pathogenicity and sexual differentiation in the human malaria parasite.

This study identifies and characterizes long non-coding RNAs (lncRNAs) in Plasmodium falciparum, revealing their role in gene regulation, pathogenicity, and sexual differentiation.

Decoding The Nuclear Genome of The Human Pathogen Babesia duncani Shed Light on its Virulence, Drug Susceptibility and Evolution among Apicomplexa

This study decodes the nuclear genome of Babesia duncani, identifies virulence factors and drug targets, and discovers potent inhibitors for treating babesiosis.

The bacterial magnesium transporter MgtA reveals highly selective interaction with specific cardiolipin species

This study shows that the bacterial magnesium transporter MgtA has functional specificity for cardiolipin species, with maximum activity achieved when combining cardiolipin 16:0 and 18:1.

Genome-wide functional analysis reveals key roles for kinesins in the mammalian and mosquito stages of the malaria parasite life cycle

The paper identifies key kinesins involved in the malaria parasite life cycle in mammalian and mosquito hosts, showing kinesin-13 is essential for growth in mammals while others are critical for mosquito transmission.

Bacterial-type plant ferroxidases tune local phosphate sensing in root development

The paper shows that bacterial-type ferroxidases in Arabidopsis thaliana modulate phosphate sensing in roots by regulating iron homeostasis and growth under phosphate limitation.

Expression levels of long noncoding natural antisense transcripts overlapping the UGT73C6 gene affect rosette size of Arabidopsis thaliana

This study identifies two lncNATs overlapping UGT73C6 in Arabidopsis thaliana that regulate rosette size by modulating cell proliferation and leaf growth through transcription factor regulation.

The essential transcriptional regulator HDP1 drives expansion of the inner membrane complex during early sexual differentiation of malaria parasites.

This study identifies HDP1 as a transcriptional regulator essential for upregulating inner membrane complex genes during early gametocytogenesis in Plasmodium falciparum.

Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation

The paper studies the dynamics of the NDC80 complex in Plasmodium berghei to reveal unique chromosome segregation mechanisms during parasite proliferation.

A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress

The paper identifies C53 as a conserved ER-phagy receptor that links autophagy with ribosome-associated quality control during ER stress in plants and mammals.

Plasmodium condensin core subunits (SMC2/SMC4) mediate atypical mitosis and are essential for parasite proliferation and transmission

Kinesin-8B controls basal body function and flagellum formation and is key to malaria parasite transmission

This study identifies kinesin-8B's role in malaria parasite flagellum formation and transmission by analyzing its localization and function during gamete development.

Plasmodium Kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission

This study identifies Plasmodium Kinesin-8X as essential for endomitotic division during oocyst development and parasite transmission.

Drug-target binding quantitatively predicts optimal antibiotic dose levels

This paper develops a computational model to predict antibiotic dose-response relationships from drug-target binding parameters and validates it with clinical isolates.

Prevalence of chronic chikungunya and associated risks factors in the French West Indies (La Martinique). A prospective cohort study

This study assesses the prevalence of chronic chikungunya and identifies risk factors associated with chronicity in a cohort of patients in La Martinique.

Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

This study uses transposon-insertion sequencing to identify genes required for EHEC growth in vitro and in vivo, revealing new factors critical for intestinal colonization.

Self-organization controls expression more than abundance of molecular components of transcription and translation in confined cell-free gene expression

This study shows that self-organization, not molecular abundance, drives expression efficiency and noise in cell-free gene expression systems.

Microtubule-associated protein IQ67 DOMAIN5 regulates interdigitation of leaf pavement cells in Arabidopsis thaliana

This study identifies IQD5 as a microtubule-associated protein regulating pavement cell shape in Arabidopsis by linking calcium signaling to interdigitation and asymmetric expansion.