Lysosomal mitochondrial interaction promotes tumor growth in squamous cell carcinoma of the head and neck
A. Gopalkrishnan, N. Wang, S. Cruz-Rangel, A. Yassin-Kassab, S. Shiva, C. Kurukulasuriya, S. P. Monga, R. J. DeBerardinis, K. Kiselyov, U. Duvvuri
This study shows that lysosomal-mitochondrial interaction (LMI) promotes tumor growth in squamous cell carcinoma of the head and neck by enhancing mitochondrial complex I activity and lysosomal function.
bioRxiv · Jun 25, 2023Cancer Biology