Author

A. Greenhough

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

K. Malik· 3 shared M. Szemes· 3 shared D. Catchpoole· 2 shared J. H. Park· 2 shared Z. Melegh· 2 shared A. Gsur· 1 shared A. Nounu· 1 shared A. T. Chan· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

K. Malik

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4 papers

Recent·Most cited

Cancer BiologybioRxivJan 11, 2021

Transcriptomic analyses of MYCN-regulated genes in anaplastic Wilms' tumour cell lines reveals oncogenic pathways and potential therapeutic vulnerabilities

M. Szemes, Z. Melegh, J. Bellamy…·K. Malik

DOI 10.3390/cancers13040656

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivAug 14, 2020

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

A. Nounu, A. Greenhough, K. J. Heesom…·G. Rennert

This study combines proteomics and Mendelian randomization to identify aspirin-targeted proteins associated with reduced colorectal cancer risk.

DOI 10.1158/1055-9965.epi-20-1176

humanproteomics

𝕏 PostBluesky

Cancer BiologybioRxivDec 27, 2018

Wnt signalling is a major determinant of neuroblastoma cell lineages

M. Szemes, A. Greenhough, K. Malik

This study uses sequencing data to show Wnt signaling influences neural crest gene regulatory networks and neuroblastoma cell lineages through PRRX1 and YAP/TAZ, and may cooperate with Hedgehog in adrenergic differentiation.

DOI 10.3389/fnmol.2019.00090

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivJan 12, 2018

Wnt signalling drives context-dependent differentiation or proliferation in neuroblastoma

M. Szemes, A. Greenhough, Z. Melegh…·K. Malik

This study identifies Wnt target genes in neuroblastoma and shows Wnt signalling can drive differentiation in some cell lines and proliferation in others.

DOI 10.1016/j.neo.2018.01.009

humanbulk RNA-seq

𝕏 PostBluesky