J. H. Park

This study shows that vitamin B2 deficiency impairs PPAR regulation of fasting glucose, and PPAR agonists can rescue this defect.

This study enhances Stx2e production in STEC 150229 by overexpressing the A subunit, resulting in higher cytotoxicity against Vero cells.

This study identifies PgfA as a periplasmic protein essential for asymmetric polar growth in mycobacteria by coordinating lipid trafficking and cell wall synthesis.

The paper reconstructs the evolutionary history of therapy-related myeloid neoplasms using chemotherapy-associated mutational signatures and identifies distinct mutational patterns linked to different chemotherapies.

This study identifies DR3 as a surface marker for thymic NKT17 cells and shows it activates these cells in vivo and in vitro.

The paper shows EP400NL forms a chromatin remodeling complex that activates PD-L1 gene expression via cMyc, suggesting it as a target for cancer immunotherapy.

The paper develops a label-free 3D segmentation method using deep learning to analyze live cells and their organelles without exogenous labels.

This paper presents a mechanistic model of tumor metabolism that identifies key principles governing metabolic heterogeneity and plasticity in cancer cells.

The paper develops a platform for single-cell immune profiling using capillary blood to study gene expression variability across individuals and time.

The paper investigates how a common SLC39A8 variant affects brain metal transport and plasma glycosylation in schizophrenia, identifying manganese-related changes and potential biomarkers.

This study shows that CAT tail aggregation in yeast causes proteotoxicity and blocks degradation of incomplete polypeptides.

This study shows that flagellin, a bacterial MAMP, can trigger either pro- or anti-inflammatory responses depending on the tissue's physiological state and context.

This study identifies Wnt target genes in neuroblastoma and shows Wnt signalling can drive differentiation in some cell lines and proliferation in others.