Animal Behavior & CognitionbioRxiv
Establishing Preclinical Withdrawal Syndrome Symptomatology Following Heroin Self-Administration in Male and Female Rats
C. D. Gipson, K. E. Dunn, A. H. Bull…·A. Hossain
This study characterizes opioid withdrawal symptoms in male and female rats following heroin self-administration and abrupt discontinuation, revealing sex-specific differences in acute and protracted withdrawal.
DOI 10.1037/pha0000375