BiochemistrybioRxiv
Discovery and Development of Novel DNA-PK Inhibitors by Targeting the unique Ku-DNA Interaction
N. S. Gavande, P. S. VanderVere-Carozza, K. S. Pawelczak…·J. J. Turchi
This study discovers and develops a new class of DNA-PK inhibitors that target the Ku-DNA interaction, enhancing the efficacy of ionizing radiation and gene editing.
DOI 10.1093/nar/gkaa934