ImmunologybioRxiv
Cell-intrinsic ceramides determine T cell function during melanoma progression
M. Hose, A. Günther, E. Naser…·W. Hansen
This study shows that ceramide levels in T cells affect their function during melanoma progression, with reduced ceramide impairing T cell responses and elevated ceramide enhancing cytotoxic activity.
DOI 10.7554/elife.83073