Regulation of cell dynamics by rapid transport of integrins through the biosynthetic pathway
M. Lerche, M. Mathieu, L. Malerod, N. M. Pedersen, H. Hamidi, M. Chastney, B. M. H. Bruininks, S. Kaptan, G. Jacquemet, I. Vattulainen, P. Roca-Cusachs, A. Brech, F. Perez, G. Boncompain, S. Miserey, J. Ivaska
This study shows that integrin transport through the biosynthetic pathway rapidly alters adhesion receptor availability, enabling localized cell spreading and focal adhesion growth.
bioRxiv · Jul 12, 2022Cell Biology