Interaction with IP6K1 supports pyrophosphorylation of substrate proteins by the inositol pyrophosphate 5-IP7
A. Hamid, J. S. Ladke, A. Shah, M. Pal, S. Ganguli, A. Singh, R. Bhandari
The paper shows that IP6K1 interacts with proteins that undergo pyrophosphorylation and with CK2, enabling coordinated pre-phosphorylation and pyrophosphorylation of target serine residues.
bioRxiv · Dec 10, 2023 · PreprintCell Biology