A spatial map of hepatic mitochondria uncovers functional heterogeneity shaped by nutrient-sensing signaling
S. W. S. Kang, R. P. Cunningham, C. B. Miller, L. A. Brown, C. M. Cultraro, A. Harned, K. Narayan, J. Hernandez, L. M. Jenkins, A. Lobanov, M. Cam, N. Porat-Shliom
The paper investigates mitochondrial heterogeneity in the liver by combining spatial proteomics and functional analysis, revealing distinct metabolic functions in periportal and pericentral regions.
bioRxiv · Apr 13, 2023Cell Biology