TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers
M. Kundu, Y. E. Greer, A. Lobanov, L. Ridnour, R. N. Donahue, Y. Ng, S. Ratnayake, D. Voeller, S. Weltz, Q. Chen, S. J. Lockett, M. Cam, D. Meerzaman, D. A. Wink, S. Lipkowitz
This study shows TRAIL treatment of TNBC cells activates the NFKB2 pathway, leading to cytokine production that enhances neutrophil chemotaxis and immune suppression.
bioRxiv · Jul 19, 2024 · PreprintCancer Biology