Author

A. Hatzioannou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

L. Boon· 2 shared P. Verginis· 2 shared A. Boumpas· 1 shared A. Delis· 1 shared A. I. Legaki· 1 shared A. S. Papaioannou· 1 shared A. Tasis· 1 shared A. Varveri· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

L. Boon

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

An Immunological Synapse Formation Between T Regulatory Cells and Cancer-Associated Fibroblasts Promotes Tumor Development

A. Varveri, M. Papadopoulou, Z. Papadovasilakis, E. B. Compeer, A. I. Legaki, A. Delis, V. Damaskou, L. Boon, S. Papadogiorgaki, M. Samiotaki, P. G. Foukas, A. Hatzioannou, T. Alissafi, M. L. Dustin, P. Verginis

This study identifies an immunosuppressive mechanism in the tumor microenvironment where SMA+ cancer-associated fibroblasts process and present tumor antigens via autophagy to form immunological synapses with Foxp3+ T regulatory cells, promoting tumor development.

bioRxiv · Dec 22, 2023 · PreprintCancer Biology

PD-L1 blockade immunotherapy rewires cancer emergency myelopoiesis

A. Boumpas, A. S. Papaioannou, P. Bousounis, M. Grigoriou, V. Bergo, I. Papafragkos, A. Tasis, M. Iskas, L. Boon, M. Makridakis, A. Vlahou, E. Gavriilaki, A. Hatzioannou, I. Mitroulis, E. Trompouki, P. Verginis

This study shows PD-L1 blockade in tumor-bearing mice targets bone marrow HSPCs, reprograms their transcriptome toward inflammation, and reduces myeloid-derived suppressor cells.

bioRxiv · Dec 20, 2023 · PreprintImmunology