ImmunologybioRxivPreprint
PD-L1 blockade immunotherapy rewires cancer emergency myelopoiesis
A. Boumpas, A. S. Papaioannou, P. Bousounis…·P. Verginis
This study shows PD-L1 blockade in tumor-bearing mice targets bone marrow HSPCs, reprograms their transcriptome toward inflammation, and reduces myeloid-derived suppressor cells.
DOI 10.1101/2023.12.20.572561