Author

A. Hoerauf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 1

Frequent Co-Authors

B. Lenz· 2 shared F. Risch· 2 shared J. Ajendra· 2 shared M. Koschel· 2 shared A. Laudisoit· 1 shared A. Vijayakumar· 1 shared A.-L. Neumann· 1 shared B. Schumak· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

B. Lenz

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3 papers

Recent·Most cited

Eosinophils are an endogenous source of IL-4 during filarial infections and contribute to the development of an optimal T helper 2 response

C. Guth, P. P. Schumacher, A. Vijayakumar, H. Borgmann, H. Balles, M. Koschel, F. Risch, B. Lenz, A. Hoerauf, M. P. Hubner, J. Ajendra

This study identifies eosinophils as a major source of IL-4 during filarial infections, showing their critical role in driving Th2 responses without affecting macrophage polarization or antibody production.

bioRxiv · Oct 26, 2023Immunology

Identification of the onchocerciasis vector in the Kakoi-Koda focus of the Democratic Republic of Congo

R. J. Post, A. Laudisoit, M. Mandro, T. Lakwo, C. Laemmer, K. Pfarr, A. Hoerauf, P. Tortosa, Y. Gomard, T. Ukety, C. Mande, L. Farovitch, U. Amazigo, D. W. Oguttu, D. Bakajika, , R. Colebunders

The paper identifies Simulium dentulosum and S. vorax as vectors of onchocerciasis in the Kakoi-Koda focus, with S. dentulosum being the main vector and S. neavei possibly having been the main vector in the past.

bioRxiv · Jul 25, 2022Ecology

Nucleic acid receptor ligands improve vaccination efficacy against the filarial nematode Litomosoides sigmodontis

J. F. Scheunemann, F. Risch, J. J. Reichwald, B. Lenz, A.-L. Neumann, S. Garbe, S. J. Frohberger, M. Koschel, J. Ajendra, M. Rothe, E. Latz, C. Coch, G. Hartmann, B. Schumak, A. Hoerauf, M. P. Hübner

This study shows that adding nucleic acid receptor agonists to a vaccine against the filarial nematode Litomosoides sigmodontis improves immune response and reduces worm burden by 73%.

bioRxiv · Jul 11, 2022 · PreprintImmunology