Author

M. Rothe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

E. Latz· 2 shared A. Bauer· 1 shared A. Heuser· 1 shared A. Hoerauf· 1 shared A. Jahn· 1 shared A.-K. Kahlert· 1 shared A.-L. Neumann· 1 shared B. Lenz· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

E. Latz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

KCNQ5 controls perivascular adipose tissue-mediated vasodilation

D. Tsvetkov, J. Schleifenbaum, Y. Wang, M. Kassmann, M. Polovitskaya, S. Schütze, M. Rothe, F. C. Luft, T. J. Jentsch, M. Gollasch

The paper identifies KCNQ5 channels as mediators of perivascular adipose tissue-mediated vasodilation by hyperpolarizing smooth muscle cells and enhancing oxylipin-induced relaxation.

bioRxiv · Jul 26, 2023Physiology

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators

J. Kuhnisch, S. Theisen, J. Dartsch, R. Fritsche-Guenther, M. Kirchner, B. Obermayer, A. Bauer, A.-K. Kahlert, M. Rothe, D. Beule, A. Heuser, P. Mertins, J. A. Kirwan, N. Berndt, C. A. MacRae, , S. Klaassen

This study investigates monoallelic Prdm16 mutation in mice, revealing sex-specific cardiac metabolic dysregulation and identifying Pyroxd2 and Pbxip1 as novel metabolic regulators.

bioRxiv · Jan 10, 2023 · PreprintPathology

Quantitative assessment of angioplasty induced vascular inflammation with 19F cardiovascular magnetic resonance imaging

F. Nienhaus, M. Walz, M. Rothe, A. Jahn, S. Pfeiler, H. L. Busch, M. Stern, C. Heiss, L. Vornholz, S. Cames, M. Cramer, V. Schrauwen-Hinderling, N. Gerdes, S. Temme, M. Roden, , F. Boenner

This study uses 19F MRI to quantify monocyte/macrophage infiltration after vascular injury with sufficient sensitivity.

bioRxiv · Nov 25, 2022 · PreprintImmunology

Nucleic acid receptor ligands improve vaccination efficacy against the filarial nematode Litomosoides sigmodontis

J. F. Scheunemann, F. Risch, J. J. Reichwald, B. Lenz, A.-L. Neumann, S. Garbe, S. J. Frohberger, M. Koschel, J. Ajendra, M. Rothe, E. Latz, C. Coch, G. Hartmann, B. Schumak, A. Hoerauf, M. P. Hübner

This study shows that adding nucleic acid receptor agonists to a vaccine against the filarial nematode Litomosoides sigmodontis improves immune response and reduces worm burden by 73%.

bioRxiv · Jul 11, 2022 · PreprintImmunology

Platelets fuel the inflammasome activation of innate immune cells

V. Rolfes, L. S. Ribeiro, I. Hawwari, L. Buotcher, N. S. Rosero, S. Maasewerd, M. L. S. Santos, S. V. Schmidt, M. Rothe, J. Stunden, L. H. Carvalho, C. J. Fontes, T. Prochnicki, M. Arditi, E. Latz, B. S. Franklin

This study shows platelets enhance inflammasome activation in immune cells, increasing IL-1β production, and identifies a platelet gene signature linked to autoinflammatory diseases.

bioRxiv · Oct 11, 2019Immunology