A. Hughes

Distinct sets of molecular characteristics define tumor-rejecting neoantigens

The paper identifies molecular features of tumor-rejecting neoantigens in cSCC and shows how they differ from non-immunogenic neoantigens.

Mitochondrial-Derived Compartments Remove Surplus Proteins from the Outer Mitochondrial Membrane

The paper identifies mitochondrial-derived compartments (MDCs) that selectively remove surplus and mistargeted proteins from the outer mitochondrial membrane.

Mitochondrial-Derived Compartments are Multilamellar Domains that Encase Membrane Cargo and Cytosol

The paper uses electron tomography and time-lapse fluorescence microscopy to show that mitochondrial-derived compartments (MDCs) form from outer mitochondrial membrane extensions that sequester membrane cargo and cytosol.

Lack of robust evidence for a Wolbachia infection in Anopheles gambiae from Burkina Faso

This study re-evaluates Wolbachia infection in Anopheles gambiae from Burkina Faso and finds low prevalence, contradicting earlier reports.

Parallel evolution of phage resistance - virulence trade - offs during in vitro and nasal Pseudomonas aeruginosa phage treatment

The paper investigates phage resistance evolution in Pseudomonas aeruginosa during in vitro and nasal treatments, finding similar resistance dynamics and reduced virulence in resistant strains.

Image Quality Causes Substantial Bias in Three-Dimensional Speckle-Tracking Echocardiography Measures

This study shows that poor image quality in 3D-STE leads to systematic underestimation of LV deformation and ejection fraction, with bias increasing as image quality worsens.

Biological control protects tropical forests

This study shows biological control of the mealybug reduced deforestation in Southeast Asia by decreasing cassava expansion.