Author

D. J. Roe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. C. Adams· 1 shared A. Hughes· 1 shared A. M. Macy· 1 shared A. R. Mangold· 1 shared B. M. Baker· 1 shared C. A. Brambley· 1 shared C. Chen· 1 shared E. S. Borden· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. C. Adams

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Distinct sets of molecular characteristics define tumor-rejecting neoantigens

A. C. Adams, A. M. Macy, E. S. Borden, L. M. Herrmann, C. A. Brambley, T. Ma, X. Li, A. Hughes, D. J. Roe, A. R. Mangold, K. H. Buetow, M. A. Wilson, B. M. Baker, K. T. Hastings

The paper identifies molecular features of tumor-rejecting neoantigens in cSCC and shows how they differ from non-immunogenic neoantigens.

bioRxiv · Feb 13, 2024Immunology

Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma

J. Yang, J. T. Lim, P. V. Santiago Raj, M. G. Corona, C. Chen, H. Khawaja, Q. Pan, G. D. Paine-Murrieta, R. G. Schnellmann, D. J. Roe, P. C. Gokhale, J. A. DeCaprio, M. Padi

This study identifies pyrvinium pamoate as a potential therapy for Merkel cell carcinoma by targeting Wnt signaling and multiple cancer vulnerabilities.

bioRxiv · Nov 1, 2023Cancer Biology