Author

A. Ishaq

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

E. Fielder· 2 shared E. Low· 2 shared S. Miwa· 2 shared T. von Zglinicki· 2 shared A. Calista· 1 shared B. Griffin· 1 shared C. Parker· 1 shared D. Jurk· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

E. Fielder

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mild uncoupling of mitochondria synergistically enhances senolytic specificity and sensitivity of BH3 mimetics

E. Fielder, A. Ishaq, E. Low, J. Laws, A. Calista, J. Castle, T. von Zglinicki, S. Miwa

This study shows that mild mitochondrial uncoupling enhances the senolytic effectiveness of BH3 mimetics in vitro and in vivo by targeting senescent cell vulnerabilities.

bioRxiv · Aug 23, 2023 · PreprintCell Biology

Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice

E. Fielder, T. Wan, G. Alimohammadiha, A. Ishaq, E. Low, M. B. Weigand, G. Kelly, C. Parker, B. Griffin, D. Jurk, V. Korolchuk, T. von Zglinicki, S. Miwa

The paper shows that short anti-senescence interventions reduce radiation-induced frailty and premature ageing in mice, improving muscle, liver function, and memory.

bioRxiv · Dec 15, 2021Cancer Biology