Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice
E. Fielder, T. Wan, G. Alimohammadiha, A. Ishaq, E. Low, M. B. Weigand, G. Kelly, C. Parker, B. Griffin, D. Jurk, V. Korolchuk, T. von Zglinicki, S. Miwa
The paper shows that short anti-senescence interventions reduce radiation-induced frailty and premature ageing in mice, improving muscle, liver function, and memory.
bioRxiv · Dec 15, 2021Cancer Biology