Suppressed Osteocyte Perilacunar / Canalicular RemodelingPlays a Causal Role in Osteoarthritis
C. M. Mazur, J. J. Woo, C. S. Yee, A. J. Fields, C. Acevedo, K. N. Bailey, T. W. Fowler, J. C. Lotz, A. Dang, A. Kuo, T. P. Vail, T. Alliston
This study shows that suppressed osteocyte perilacunar/canalicular remodeling causes osteoarthritis by impairing cartilage homeostasis in humans and mice.
bioRxiv · Jan 31, 2019Physiology