ImmunologybioRxiv
Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain
M. D. Gray, J. Feng, C. E. Weidle…·L. Stamatatos
The paper identifies an antibody from a clinical trial that binds a different HIV-1 Env domain than VRC01-class antibodies and shows that epitope switching requires specific CDR changes.
DOI 10.1126/sciadv.abm3948