Impaired peroxisomal import in Drosophila hepatocyte-like cells induces cardiac dysfunction through the pro-inflammatory cytokine Upd3
K. Huang, T. Miao, K. Chang, P. Kang, Q. Jiang, A. J. Simmonds, F. Di Cara, H. Bai
This study shows that impaired peroxisomal import in Drosophila oenocytes increases Upd3, causing cardiac arrhythmia, and that restoring peroxisomal import prevents this effect.
bioRxiv · Jun 3, 2019 · PreprintPhysiology