An Immune Cell Atlas Reveals Dynamic COVID-19 Specific Neutrophil Programming Amenable to Dexamethasone Therapy
S. Sinha, N. Rosin, R. Arora, E. Labit, A. Jaffer, L. Cao, R. Farias, A. P. Nguyen, L. G. N. de Almeida, A. Dufour, A. Bromley, B. McDonald, M. Gillrie, M. J. Fritzler, B. Yipp, J. Biernaskie
This study identifies distinct neutrophil states in COVID-19 compared to bacterial ARDS and shows dexamethasone alters these states, reducing mortality risk.
bioRxiv · Apr 18, 2021Immunology