The intensity of the immune response to LPS and E. coli regulates the induction of preterm labor in Rhesus Macaques
M. Cappelletti, P. Presicce, F. Ma, P. Senthamaraikannan, L. Miller, M. Pellegrini, A. Jobe, S. Divanovic, S. S. Way, C. Chougnet, S. Kallapur
This study shows that live E. coli induces stronger immune responses, including higher IL6 and prostaglandin levels, leading to preterm labor in Rhesus macaques compared to LPS.
bioRxiv · Jan 7, 2021 · PreprintImmunology