Cancer BiologybioRxivPreprint
Post-transcriptional gene regulation by the RNA binding protein IGF2BP3 is critical for MLL-AF4 mediated leukemogenesis
T. M. Tran, J. Philipp, J. Bassi…·D. S. Rao
This study identifies IGF2BP3 as a critical regulator of MLL-AF4-driven leukemogenesis, showing its role in enhancing disease progression and identifying it as a potential therapeutic target.
DOI 10.1101/2020.12.20.423624