A. Karp

ERK5 Signaling is Required for Type III IFN-mediated Mucosal Antiviral Responses

The paper identifies ERK5 as a potentiator of STAT1 activation and ISG expression, enhancing type III IFN-mediated antiviral responses in epithelial cells.

MEF2A suppresses replicative stress responses that trigger DDX41-dependent IFN production

This study shows MEF2A suppresses type I IFN production by preventing R-loop accumulation and DDX41/STING pathway activation in response to replicative stress.