Author

A. Karunarathne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Wijayaratna· 2 shared M. Tennakoon· 2 shared W. Thotamune· 2 shared A. Terakita· 1 shared D. Kankanamge· 1 shared F. Fanelli· 1 shared F. Sacchetta· 1 shared J. L. Payton· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

D. Wijayaratna

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 7, 2023

Engineered blue-shifted melanopsins for subcellular optogenetics

D. Wijayaratna, F. Sacchetta, L. Pedraza Gonzalez…·A. Karunarathne

This paper engineers blue-shifted melanopsin mutants using computational methods to enable subcellular optogenetic control without red light activation.

DOI 10.1101/2023.10.07.561352

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintJul 4, 2023

CaaX-motif adjacent residues control G protein prenylation under suboptimal conditions

M. Tennakoon, W. Thotamune, J. L. Payton, A. Karunarathne

The paper investigates how specific residues near the CaaX-motif regulate G protein prenylation and membrane interactions under suboptimal conditions, explaining differential statin effects on G protein signaling.

DOI 10.1101/2023.07.04.547731

proteomicsexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintAug 31, 2022

Molecular regulation of GPCR-G-protein-governed PIP3 generation and its adaptation

D. Wijayaratna, K. Ratnayake, S. Ubeysinghe…·A. Karunarathne

The paper investigates how GPCR activation leads to PIP3 generation and its temporal regulation through G protein subunit-dependent adaptation.

DOI 10.1101/2022.08.31.506078

experimental assaycell signaling & trafficking

𝕏 PostBluesky