Author

A. Kaykas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

K. A. Worringer· 2 shared S. Kommineni· 2 shared A. K. Mir· 1 shared B. Altshuler· 1 shared C. Barske· 1 shared C. J. Faraday· 1 shared C. L. Hsieh· 1 shared C. Russ· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

K. A. Worringer

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Author profile →

2 papers

Recent·Most cited

Genome-Scale CRISPR Screening Identifies Novel Human Pluripotent Gene Networks

R. J. Ihry, M. R. Salick, D. Ho, M. Sondey, S. Kommineni, S. Paula, J. Raymond, E. Frias, K. A. Worringer, C. Russ, J. Reece-Hoyes, B. Altshuler, R. Randhawa, Z. Yang, G. McAllister, , A. Kaykas

The paper uses CRISPR screening to identify novel genes involved in human pluripotent stem cell properties.

bioRxiv · May 16, 2018Cell Biology

ADAM17 Is The Main Sheddase For The Generation Of Human Triggering Receptor Expressed In Myeloid Cells (hTREM2) Ectodomain And Cleaves TREM2 After Histidine 157

D. Feuerbach, P. Schindler, C. Barske, S. Joller, E. Beng-Louka, K. A. Worringer, S. Kommineni, A. Kaykas, D. J. Ho, C. Ye, K. Welzenbach, G. Elain, L. Klein, I. Brzak, A. K. Mir, , U. Neumann

This study identifies ADAM17 as the primary sheddase for TREM2 ectodomain release and determines the cleavage site at histidine 157.

bioRxiv · May 3, 2017Cell Biology