Author

P. Tharmapalan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Zhang· 3 shared C. W. McCloskey· 2 shared F. Vyas· 2 shared M. Waas· 2 shared R. Khokha· 2 shared T. Kislinger· 2 shared A. Khoo· 1 shared A. Kuttanamkuzhi· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

B. Zhang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FABP7 Progenitors are a Targetable Metabolic Root in the BRCA1 Breast

C. W. McCloskey, B. Zhang, M. Waas, G. Abazari, F. Vyas, K. Aliar, P. Tharmapalan, A. Kuttanamkuzhi, S. Narala, J. Cruikshank, S. O. P. Hofer, H. W. Jackson, T. Kislinger, H. K. Berman, R. Khokha

This study identifies FABP7 progenitors as a targetable metabolic root in BRCA1 breast cancer, showing their dysregulation and potential inhibition via fatty acid metabolism disruption.

bioRxiv · Nov 2, 2023 · PreprintCell Biology

Droplet based low input proteomic platform for rare cell populations

M. Waas, A. Khoo, P. Tharmapalan, C. W. McCloskey, M. Govindarajan, B. Zhang, S. Khan, P. Waterhouse, R. Khokha, T. Kislinger

DROPPS enables high-fidelity proteomic profiling of rare cell populations with low input, revealing CD36 as a marker of progenitor capacity in mammary basal cells.

bioRxiv · Sep 11, 2023 · PreprintBiochemistry

Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice

L. M. Podmore, Y. Poloz, C. Iorio, S. Mouaaz, K. Nixon, P. Smirnov, B. McDonnell, S. Lam, B. Zhang, P. Tharmapalan, S. Sarkar, F. Vyas, M. Ennis, R. Dowling, V. Stambolic

This study shows that insulin receptor loss delays mammary tumor onset and burden in mouse models, without affecting progression or metastasis.

bioRxiv · May 6, 2022Cancer Biology