Stereotypic expansion of Tregulatory and Th17 cells during infancy is disrupted by HIV exposure and gut epithelial damage.
S. Dzanibe, K. Lennard, A. Kiravu, M. S. S. Seabrook, B. Alinde, S. P. Holmes, C. A. Blish, H. B. Jaspan, C. M. Gray
The paper examines Treg and Th17 cell dynamics in infants, finding HIV exposure disrupts their stereotypic expansion and correlates with gut damage.
bioRxiv · May 3, 2021Immunology