H. B. Jaspan

This paper develops a non-invasive method using menstrual discs to sample immune cells from the female genital tract, demonstrating consistent T cell populations across days within individuals.

This study shows that HIV/ARV-exposed uninfected infants have reduced T cell receptor diversity and altered immune development, increasing infection risk.

The paper analyzes the foreskin microbiome and host gene expression in adolescents from South Africa and Uganda, finding no treatment effect on bacterial communities but inverse correlations between bacterial abundance and inflammatory gene expression.

The paper examines Treg and Th17 cell dynamics in infants, finding HIV exposure disrupts their stereotypic expansion and correlates with gut damage.

The paper examines factors affecting maternal microchimerism (MMc) in infants and its impact on T cell immunity following BCG vaccination.

This study uses metaproteomics to link microbial function and inflammation in the female genital tract of South African women at high HIV risk, finding that reduced cell wall organization and peptidoglycan biosynthesis are associated with high inflammation.

The paper investigates crAssphage transmission and genomic evolution in South African mother-infant dyads, finding evidence of vertical transmission and positive selection in phage genes correlated with bacterial abundance.

This study meta-analyzes seven studies to show that exclusive breastfeeding increases gut microbiota diversity and specific metabolic pathways while reducing others, with benefits persisting beyond six months.