Author

A. Klindziuk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1

Frequent Co-Authors

A. B. Kolomeisky· 1 shared A. Davtyan· 1 shared A. Kolomeisky· 1 shared A. Saeedi· 1 shared B. Meadowcroft· 1 shared D. S. Yang· 1 shared M. Fathi· 1 shared M. Safari· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

A. B. Kolomeisky

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2 papers

Recent·Most cited

Mesoscopic Liquid Clusters Represent a Distinct Condensate of Mutant p53

P. G. Vekilov, D. S. Yang, A. Saeedi, A. Davtyan, M. Fathi, M. Safari, A. Klindziuk, S. Barton, N. Varadarajan, A. Kolomeisky

This study investigates the phase behavior of mutant p53, showing it forms mesoscopic liquid clusters that facilitate amyloid fibril nucleation and revealing that structural destabilization drives condensation.

bioRxiv · Feb 4, 2020 · PreprintBiophysics

Mechanochemical Model of Transcriptional Bursting

A. Klindziuk, B. Meadowcroft, A. B. Kolomeisky

This paper develops a mechano-chemical model of transcriptional bursting, showing that DNA supercoiling and gyrase activity drive stochastic RNA production and explain phenotypic variability.

bioRxiv · Oct 11, 2019Biophysics