BiochemistrybioRxiv
The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion.
K. M. Feher, A. Kolbanovskiy, A. Durandin…·N. E. Geacintov
This study shows that XPC-RAD23B does not bind to DNA lesions with a missing nucleotide opposite the lesion, due to structural stabilization preventing XPC binding.
DOI 10.1016/j.dnarep.2020.102985