Author

S. Broyde

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 4 Assay:DNA methylation· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:structural biology· 2

Frequent Co-Authors

H. Mu· 4 shared J. H. Min· 4 shared A. Tavakoli· 3 shared D. Paul· 3 shared A. Ansari· 2 shared C. He· 2 shared Q. Dai· 2 shared A. Durandin· 1 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

H. Mu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tethering-facilitated DNA 'opening' and complementary roles of β-hairpin motifs in the Rad4/XPC DNA damage sensor protein

D. Paul, H. Mu, A. Tavakoli, Q. Dai, X. Chen, S. Chakraborty, C. He, A. Ansari, S. Broyde, J. H. Min

This study shows Rad4/XPC can open undamaged DNA in solution without specific β-hairpin motifs and reveals dynamic conformations of open DNA through crystal structures and fluorescence analysis.

bioRxiv · Sep 28, 2020Biochemistry

Light-induced modulation of DNA recognition by the Rad4/XPC damage sensor protein

A. Tavakoli, D. Paul, H. Mu, J. Kuchlyan, S. Baral, A. Ansari, S. Broyde, J. H. Min

This paper shows that light can control DNA binding by the Rad4/XPC repair complex using photoswitchable DNA, revealing structural changes in DNA upon binding.

bioRxiv · Sep 28, 2020Biochemistry

The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion.

K. M. Feher, A. Kolbanovskiy, A. Durandin, Y. Shim, J. H. Min, Y. C. Lee, V. Shafirovich, H. Mu, S. Broyde, N. E. Geacintov

This study shows that XPC-RAD23B does not bind to DNA lesions with a missing nucleotide opposite the lesion, due to structural stabilization preventing XPC binding.

bioRxiv · Sep 14, 2020Biochemistry

Impact of DNA sequences in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex

J. H. Min, S. Broyde, D. Paul, H. Mu, Q. Dai, A. Tavakoli, C. He

This study shows that DNA sequences affect how Rad4/XPC opens DNA duplexes, with some sequences resisting opening despite prolonged Rad4 binding.

bioRxiv · Jan 16, 2020Biochemistry