Author

A. La Greca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2

Frequent Co-Authors

S. G. Miriuka· 5 shared A. Lombardi· 4 shared A. Waisman· 4 shared C. Luzzani· 4 shared L. N. Moro· 4 shared A. Norris· 2 shared G. Sevlever· 2 shared M. A. Scarafia· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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5 shared papersCell Biology

S. G. Miriuka

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

In silico labeling enables kinetic myelination assay in brightfield

J. Fang, E. Y. Bergsdorf, V. Unterreiner, A. La Greca, O. Dergai, I. Claerr, N.-H. Luong-Nguyen, I. Galuba, I. Moutsatsos, S. Hatakeyama, P. Groot-Kormelink, F. Zeng, X. Zhang

This paper develops an in-silico labeling method using a generative adversarial network to predict fluorescent images from brightfield images, enabling kinetic myelination assays.

bioRxiv · Sep 11, 2022 · PreprintCell Biology

Small extracellular vesicles from iPSC-MSC lose their regenerative potential upon UV-C irradiation

M. C. Biani, A. Lombardi, A. Norris, P. Bucci, A. La Greca, A. Waisman, L. N. Moro, G. Sevlever, J. Montanari, S. G. Miriuka, C. Luzzani

This study shows that UV-C irradiation of iPSC-MSC alters the cargo of secreted small EVs, reducing their ability to promote cell migration.

bioRxiv · Sep 27, 2021 · PreprintCell Biology

Effects of bacterial lipopolysaccharide and Shiga Toxin on induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells

D. Martire-Greco, A. La Greca, L. Castillo Montanez, C. Biani, A. Lombardi, F. Birnberg-Weiss, A. Norris, F. Sacerdoti, M. M. Amaral, N. Rodrigues-Rodriguez, J. R. Pittaluga, V. A. Furmento, V. I. Landoni, S. G. Miriuka, C. D. Luzzani, G. C. Fernandez

This study examines how LPS and Stx affect iPSC-MSC and their ability to repair endothelial damage, showing LPS induces inflammation while LPS+Stx impairs repair.

bioRxiv · Sep 7, 2021Immunology

HLA-G gene editing: a novel therapeutic alternative in cancer immunotherapy

M. B. Palma, D. Tronik-Le Roux, G. Amin, S. Castaneda, A. M. Mobbs, M. A. Scarafia, A. La Greca, M. Daouya, I. Poras, A. M. Inda, L. N. Moro, E. D. Carosella, M. N. Garcia, S. G. Miriuka

This study uses CRISPR/Cas9 to downregulate HLA-G in tumor cell lines, showing enhanced immune response and proposing gene editing as a novel immunotherapy approach.

bioRxiv · Jan 21, 2021 · PreprintCancer Biology

Single cell transfection of human induced pluripotent stem cells using a droplet-based microfluidic system.

C. Perez, A. Sanluis-Verdes, A. Waisman, A. Lombardi, G. ROSERO, A. La Greca, S. Bhansali, N. Bourguignon, C. Luzzani, M. Perez, S. Miriuka, B. Lerner

The paper presents a droplet-based microfluidic system for transfecting human-induced pluripotent stem cells, showing high efficiency and cost-effectiveness compared to other methods.

bioRxiv · Jun 9, 2020 · PreprintBioengineering

Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT

C. Aban, A. Lombardi, G. Neiman, M. C. Biani, A. La Greca, A. Waisman, L. N. Moro, G. E. Sevlever, S. G. Miriuka, C. Luzzani

This study shows that reducing E-cadherin in human embryonic stem cells leads to partial EMT with retained undifferentiated features and altered gene expression.

bioRxiv · May 18, 2020Cell Biology

celldeath: a tool for detection of cell death in transmitted light microscopy images by deep learning-based visual recognition

A. La Greca, N. Perez, S. Castaneda, P. M. Milone, M. A. Scarafia, A. M. Möbbs, A. Waisman, L. N. Moro, G. Sevlever, C. Luzzani, S. G. Miriuka

The paper develops a deep learning tool to detect cell death in microscopy images, showing high accuracy and outperforming human detection.

bioRxiv · Mar 22, 2020 · PreprintCell Biology