Author

A. Lak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

J. Lipfert· 2 shared M. S. Chowdhury· 2 shared M. Schilling· 2 shared T. Viereck· 2 shared A. Narducci· 1 shared A. V. Baptist· 1 shared C. Korosy· 1 shared C. Pauer· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

J. Lipfert

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Determination of Absolute Intramolecular Distances in Proteins by Anomalous X-ray Scattering Interferometry

S. Stubhan, A. V. Baptist, C. Korosy, A. Narducci, G. G. Moya Munoz, N. Wendler, A. Lak, M. Sztucki, T. Cordes, J. Lipfert

This study introduces AXSI for measuring absolute intramolecular distances in proteins, validated against single-molecule FRET, showing its effectiveness under various solution conditions.

bioRxiv · Feb 9, 2024 · PreprintBiophysics

Cooperative dynamics of DNA grafted magnetic nanoparticles optimize magnetic biosensing and coupling to DNA origami

A. Lak, Y. Wang, P. J. Kolbeck, C. Pauer, M. S. Chowdhury, M. Cassani, F. Ludwig, T. Viereck, F. Selbach, P. Tinnefeld, M. Schilling, T. Liedl, J. Tavacoli, J. Lipfert

This study shows that DNA grafting density on magnetic nanoparticles affects their dynamics and biosensing performance, with optimal sensitivity at intermediate densities.

Nanoscale · Jan 1, 2024Peer-reviewedBiochemistry

Amplification and extraction free quantitative detection of viral nucleic acids and single-base mismatches using magnetic signal amplification circuit

E. L. Roesch, R. Sack, M. S. Chowdhury, F. Wolgast, M. Schilling, T. Viereck, A. Lak

This paper introduces a magnetic signal amplification circuit for detecting viral nucleic acids and single-base mismatches without amplification or extraction, achieving higher sensitivity than existing methods.

bioRxiv · Dec 24, 2022 · PreprintBiochemistry