Author

A. Lampert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 4 Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

R. Hausmann· 2 shared A. Korngreen· 1 shared A. Maxion· 1 shared A. Obrecht· 1 shared A. Piergentili· 1 shared B. Haddad· 1 shared B. Namer· 1 shared E. Leipold· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersPharmacology & Toxicology

R. Hausmann

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Author profile →

4 papers

Recent·Most cited

Depletion of membrane cholesterol modifies structure, dynamic and activation of Nav1.7

S. Albani, V. S. B. Eswaran, A. Piergentili, P. C. T. d. Souza, A. Lampert, G. Rossetti

This study shows that cholesterol depletion alters Nav1.7 structure and function, affecting its gating and drug response, with implications for pain management.

bioRxiv · Feb 21, 2024Physiology

Sodium channels expressed in nociceptors contribute distinctly to action potential subthreshold phase, upstroke and shoulder

P. A. Köster, E. Leipold, J. Tigerholm, A. Maxion, B. Namer, T. Stiehl, A. Lampert

The paper functionally characterizes sodium channels in nociceptors using patch-clamp and computational models, revealing Nav1.9's role in action potential upstroke and shoulder.

bioRxiv · Sep 3, 2023Physiology

Diclofenac and other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are Competitive Antagonists of the human P2X3 Receptor

L. Grohs, L. Cheng, S. Coenen, B. Haddad, A. Obrecht, I. Toklucu, L. Ernst, J. Koerner, G. Schmalzing, A. Lampert, J.-P. Machtens, R. Hausmann

This study identifies diclofenac and other NSAIDs as competitive antagonists of the human P2X3 receptor, with diclofenac showing strong inhibition of hP2X3R and hP2X2/3R.

bioRxiv · Dec 19, 2022 · PreprintPharmacology & Toxicology

Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents

S. Kriegeskorte, R. Bott, M. Hampl, A. Korngreen, R. Hausmann, A. Lampert

This study examines how temperature affects sodium channel gating and persistent currents in Nav1.3, Nav1.5, Nav1.6, and Nav1.7, with specific focus on mutations linked to pain disorders.

bioRxiv · Dec 19, 2022Physiology