Author

A. Lane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Brugulat Panes· 1 shared A. J. Hardcastle· 1 shared A. Pekosz· 1 shared D. Ottaviani· 1 shared E. Rheinbay· 1 shared H. Kulaga· 1 shared I. Mitsiades· 1 shared J. C. Gardner· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Brugulat Panes

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of chromosome Y in primary tumors

M. Qi, J. Pang, I. Mitsiades, A. Lane, E. Rheinbay

The paper analyzes LOY in over 5,000 male tumors from TCGA, showing variation by tumor type and identifying LOY as a potential driver or passenger event with therapeutic implications in uveal melanoma.

bioRxiv · Aug 22, 2022Cancer Biology

Evolution of nasal and olfactory infection characteristics of SARS-CoV-2 variants

M. Chen, A. Pekosz, J. Villano, W. Shen, R. Zhou, H. Kulaga, Z. Li, S. E. Beck, K. W. Witwer, J. Mankowski, M. Ramanathan, N. Rowan, A. Lane

This study examines how SARS-CoV-2 variants infect nasal and olfactory tissues, showing differences in tropism, immune response, and regeneration across age groups.

bioRxiv · Apr 12, 2022Pathology

The role of Musashi-1 in CEP290 c.2991+1655A>G cryptic exon splicing in Leber Congenital Amaurosis

D. Ottaviani, A. Lane, K. Jovanovic, J. C. Gardner, P. E. Sladen, K. L. Hau, A. Brugulat Panes, R. Guarascio, A. J. Hardcastle, M. E. Cheetham

This study investigates the role of Musashi-1 in alternative splicing of CEP290 in human retinal organoids and finds it does not drive the inclusion of the LCA10-associated cryptic exon.

bioRxiv · Aug 4, 2021 · PreprintCell Biology