Mapping Endothelial-Macrophage Interactions in Diabetic Vasculature: Role of TREM2 in Vascular Inflammation and Ischemic Response
N. K. Malhi, Y. Luo, X. Tang, R. S. Chadha, A. Tapia, D. Yuan, S. Yin, M. Chen, X. Liu, M. Reddy, M. Qi, L. Wei, J. P. Cooke, E. Lee, R. Natarajan, , Z. B. Chen
This study maps endothelial-macrophage interactions in diabetic vasculature using single-cell and spatial transcriptomics, identifying TREM2 as a key driver of vascular inflammation and ischemic response in diabetes.
bioRxiv · May 14, 2024 · PreprintCell Biology