Author

A. Leech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Daab· 1 shared A. J. Wollman· 1 shared A. Kovaltsuk· 1 shared A. Payne-Dwyer· 1 shared A. Syeda· 1 shared B. Strongitharm· 1 shared C. Caldas· 1 shared C. Guy· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. Daab

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structure, substrate selectivity determinants and membrane interactions of a Glutamate-specific TAXI TRAP binding protein from Vibrio cholerae.

J. F. Davies, A. Daab, N. Massouh, C. Kirkland, B. Strongitharm, A. Leech, M. Farre, G. H. Thomas, C. Mulligan

This paper structurally and biochemically characterizes a glutamate-specific TRAP transporter from V. cholerae, revealing its substrate selectivity and membrane interaction mechanisms.

bioRxiv · Mar 22, 2024 · PreprintBiochemistry

Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks

A. J. Wollman, A. Syeda, J. Howard, A. Payne-Dwyer, A. Leech, D. Warecka, C. Guy, P. McGlynn, M. Hawkins, M. C. Leake

The paper shows UvrD forms tetramers and associates with replication forks due to frequent nucleoprotein blocks, distinct from Rep's recruitment mechanism.

bioRxiv · Feb 22, 2021 · PreprintBiophysics

Deep sequencing of B cell receptor repertoires from COVID-19 patients reveals strong convergent immune signatures

J. D. Galson, S. Schaetzle, R. J. M. Bashford-Rogers, M. I. J. Raybould, A. Kovaltsuk, G. J. Kilpatrick, R. Minter, D. K. Finch, J. Dias, L. James, G. Thomas, W.-Y. J. Lee, J. Betley, O. Cavlan, A. Leech, , J. Osbourn

The paper analyzes B cell receptor repertoires from COVID-19 patients to identify convergent immune signatures associated with disease outcome.

bioRxiv · May 20, 2020Immunology