Maturation of Human Long-lived Plasma Cells Results in Resistance to Apoptosis by Transcriptional and Epigenetic Regulation
C. J. Joyner, A. Ley, D. Nguyen, M. Ali, A. Corrado, C. Tipton, C. Scharer, T. Mi, M. C. Woodruff, J. Hom, J. M. Boss, M. Duan, G. Gibson, D. Roberts, J. Andrews, , F. E.-H. Lee
This study shows human blood ASCs undergo transcriptional and epigenetic changes in the BM microniche to become apoptotic-resistant LLPC.
bioRxiv · May 22, 2021 · PreprintImmunology