J. Andrews

Majority of human circulating plasmablasts stop blasting: A probable misnomer

The study shows most blood plasmablasts are not actively dividing, suggesting the term 'plasmablast' may be misleading.

Rapid mode switching facilitates the growth of Trichodesmium: A model analysis.

This study develops a metabolic model of Trichodesmium showing that rapid switching between photosynthetic and non-photosynthetic states enhances growth by improving metabolic efficiency.

Structure and dynamics of endogenous protein complexes in human heart tissue captured by native nanoproteomics

This study develops a native nanoproteomics method to characterize the structure and dynamics of endogenous cardiac troponin complexes in human heart tissue using native top-down mass spectrometry.

Quantifying Local Perceptions of Environmental Change and Links to Community-Based Conservation Practices

The paper quantifies how perceptions of mangrove decline influence conservation behaviors in Tanzanian communities, showing that perceived risk of theft can reduce support for conservation.

Causal attribution of agricultural expansion in a small island system using approximate Bayesian computation

This paper uses approximate Bayesian computation to assess the causal drivers of agricultural expansion in Pemba, Tanzania, showing how soil degradation may have driven deforestation rather than external market forces.

Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses

The study maps human bone marrow plasma cell heterogeneity using single-cell transcriptomics, revealing maturation pathways and molecular features of long-lived plasma cells.

Maturation of Human Long-lived Plasma Cells Results in Resistance to Apoptosis by Transcriptional and Epigenetic Regulation

This study shows human blood ASCs undergo transcriptional and epigenetic changes in the BM microniche to become apoptotic-resistant LLPC.

Subjugating Translational Inhibition in Response to Ribosomal Protein Insufficiency by a Herpesvirus Ribosome-Associated Protein

This study identifies VP22 as a herpesvirus protein that compensates for ribosomal protein insufficiency to support viral protein synthesis during infection.

In vitro Evolution of Antibody Affinity via Insertional Mutagenesis Scanning of an Entire Antibody Variable Region

This paper demonstrates that insertional mutagenesis can enhance antibody affinity, achieving a 256-fold improvement in an anti-IL-13 antibody through InDel mutagenesis combined with point mutations.