G. Gibson

Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses

The study maps human bone marrow plasma cell heterogeneity using single-cell transcriptomics, revealing maturation pathways and molecular features of long-lived plasma cells.

Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies

The paper structures and characterizes Lassa virus glycoproteins from multiple lineages and identifies neutralizing antibodies that target conserved epitopes.

Affinity-matured homotypic interactions induce spectrum of PfCSP-antibody structures that influence protection from malaria infection

The paper analyzes structural and functional properties of antibodies targeting PfCSP, showing how homotypic interactions and affinity maturation influence protection against malaria.

Behavioural analysis of swarming mosquitoes reveals higher hearing sensitivity than previously measured with electrophysiology methods

This study measures mosquito hearing thresholds behaviorally, finding lower sensitivity than electrophysiological methods.

Maturation of Human Long-lived Plasma Cells Results in Resistance to Apoptosis by Transcriptional and Epigenetic Regulation

This study shows human blood ASCs undergo transcriptional and epigenetic changes in the BM microniche to become apoptotic-resistant LLPC.

Evolutionary rate covariation identifies SLC30A9 (ZnT9) as a mitochondrial zinc transporter.

The paper uses evolutionary rate covariation to predict the mitochondrial localization of SLC30A9, which is confirmed experimentally as a zinc exporter.

Single-Cell Transcriptomic Attributes and Unbiased Computational Modeling for the Prediction of Immunomodulatory Potency of Mesenchymal Stromal Cells

This study uses single-cell RNA-seq and computational models to identify transcriptomic attributes predicting immunomodulatory potency of mesenchymal stromal cells.

Single-Cell RNAseq of Out-of-Thaw Mesenchymal Stromal Cells Shows Striking Tissue-of-Origin Differences and Inter-donor Cell-Cycle Variations

This study compares single-cell transcriptomes of out-of-thaw mesenchymal stromal cells from bone marrow and cord tissue, revealing tissue-of-origin differences and inter-donor cell-cycle variations.

Mosquito sound communication: are male swarms loud enough to attract females?

The paper tests if male mosquito swarms produce sounds loud enough to attract females at long distances and finds females do not respond to sounds up to 48 dB SPL.

Holographic optical trapping Raman micro-spectroscopy for interacting live cells

The paper introduces a combined holographic optical tweezers and confocal Raman spectroscopy system for manipulating and measuring live cells with high resolution.