HIV-specific CD8 T cells from elite controllers have an epigenetic imprint that preserves effector functions
A. B. Frias, R. L. Rutishauser, A. A. Sharma, T. Mi, C. Zebley, C. M. Constantz, H. A. Abdelsamed, M. Stone, M. P. Busch, S. Deeks, R.-P. Sekaly, B. Youngblood
This study identifies epigenetic and transcriptional features in HIV-specific CD8 T cells from elite controllers that support long-lived effector functions and developmental potential.
bioRxiv · Sep 28, 2021 · PreprintImmunology