Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5
T. Harrison, N. Alam, B. Farrell, D. Quinkert, A. Lias, L. King, S. J. Draper, M. K. Higgins, I. Campeotto
This paper designs a malaria vaccine immunogen using structure-guided methods to present a single epitope from PfRH5, showing improved antibody response in rats compared to PfRH5 alone.
bioRxiv · Feb 29, 2024Immunology