Author

A. Lita

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

M. Larion· 2 shared M. R. Gilbert· 2 shared T. Dowdy· 2 shared V. Ruiz-Rodado· 2 shared A. Dios-Esponera· 1 shared A. Kuzmin· 1 shared A. Pliss· 1 shared C. Burks· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

M. Larion

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2 papers

Recent·Most cited

Cysteine is a limiting factor for glioma proliferation and survival

M. Larion, V. Ruiz-Rodado, T. Dowdy, A. Lita, T. Kramp, M. Zhang, J. Jung, A. Dios-Esponera, C. C. Herold-Mende, K. Camphausen, M. R. Gilbert

This study shows that glioma cells depend on exogenous cysteine/cystine, and dietary restriction extends survival in a mouse model, though tumors can later compensate by synthesizing glutathione.

bioRxiv · Jan 8, 2021Cancer Biology

IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids

M. Larion, A. Lita, A. Pliss, A. Kuzmin, T. Yamasaki, L. Zhang, T. Dowdy, C. Burks, N. de Val, O. Celiku, V. Ruiz-Rodado, E.-R. Nicoli, M. Kruhlak, T. Andresson, S. Das, , P. N. Prasad

This paper identifies lipid imbalances caused by IDH1 mutations that lead to organelle dysfunction, with therapeutic implications for glioma treatment.

bioRxiv · Mar 20, 2020Cancer Biology