Cancer BiologybioRxiv
Cysteine is a limiting factor for glioma proliferation and survival
M. Larion, V. Ruiz-Rodado, T. Dowdy…·M. R. Gilbert
This study shows that glioma cells depend on exogenous cysteine/cystine, and dietary restriction extends survival in a mouse model, though tumors can later compensate by synthesizing glutathione.
DOI 10.1002/1878-0261.13148