Author

A. Local

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Dubrovskiy· 1 shared A. Shakya· 1 shared C. E. Schwartz· 1 shared G. Rajaraman· 1 shared H. Hu· 1 shared J. Cho· 1 shared J. M. Ellis· 1 shared J. Malley· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Dubrovskiy

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo.

S. A. Saenz, A. Local, T. Carr, A. Shakya, S. Koul, H. Hu, L. Chourb, J. Stedman, J. Malley, L. A. DAgostino, V. Shanmugasundaram, J. Malona, C. E. Schwartz, L. Beebe, M. Clements, , J. M. Ellis

The paper develops three RORγt inhibitors that reduce Th17 differentiation and inflammation in vivo and inhibit tumor growth in PDAC organoids.

bioRxiv · Feb 19, 2021 · PreprintImmunology